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Treatment When ingestion of a potential hepatotoxin (e.g., toxic mushrooms, Sago palms) has occurred within the preceding 8 hours, general procedures for GI decontamination are recommended, including induction of emesis or gastric lavage (within first 3 hours), followed by administration of activated charcoal (1 to 3 g/kg).126, 139 Induction of vomiting is contraindicated if the patient is comatose or debilitated in such a way that the gag reflex is diminished, which could predispose to aspiration pneumonia
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Furthermore, ethosomes enable a synergistic approach that combines plant extracts with conventional chemical drugs, resulting in extended therapeutic activity, reduced side effects, and minimized drug resistance [134, 135]
